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Nigro protocol : ウィキペディア英語版
Nigro protocol
Nigro protocol is the pre-operative use of chemotherapy with 5-fluorouracil and mitomycin and medical radiation for squamous cell carcinomas of the anal canal of less than 5 cm, followed by surgical excision if necessary.〔〔 Specifically, in the protocol, the patient receives 30 Gy of radiation over a three-week period, as well as continuous administration of fluorouracil for the first four days and on days 29-32, with the mitomycin administered on the first day of treatment. It is named after Norman Nigro, who developed it in the mid-1970s. In cases of patients who still have residual disease after receiving the procotol, they should undergo salvage APR (abdomino-perineal resection) four to six weeks after therapy.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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